Wiskott-Aldrich syndrome (WAS) is a rare X-linked recessive condition characterized by eczema, recurrent infections, autoimmunity, and malignancies.
It is seen almost exclusively in m...
Typical presentation is a boy with early-onset thrombocytopenia, small platelet size, atopic dermatitis, and frequent infections.
Triad of mucosal bleeding/petechiae, eczema, and recurrent ot...
Treatment approaches are variable for this pleomorphic, rare disease (1).
HSCT, from bone marrow or cord blood, achieved a 75% 7-year disease-free survival in a retrospective ...
Avoid contact sports and prevent head injuries.
Avoid crowds.
No live-virus vaccinations
Aldrich RA, Steinberg AG, Campbell DC. Pedigree demonstrating a sex-linked recessive condition characterized by draining ears, eczematoid dermatitis and bloody diarrhea. Pediatrics....
Rare; consider WAS if prolonged bleeding following circumcision and in children with recurrent infections, eczema, and low platelet counts.
Without HSCT, death usually occurs between th...
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