Wiskott-Aldrich syndrome (WAS) is a rare X-linked recessive condition characterized by eczema, immune deficiency, and microthrombocytopenia (1).
Clinically it presents as severe ecze...
Should be suspected in a male with microthrombocytopenia and excessive bruising/bleeding
Definitive diagnosis: male patient with microthrombocytopenia (platelet <70,000/mm3) and one of the...
Avoid contact sports and prevent head injuries
Avoid medications that interfere with platelet function
Frecha C, Toscano MG, Costa C, et al. Improved lentiviral vectors for Wiskott-Aldrich syndrome gene therapy mimic endogenous expression profiles throug...
Rare, X-linked; consider WAS if prolonged bleeding following circumcision and in children with recurrent infections, eczema, and low platelet counts.
HSCT may be curative
Mnemonic (TIME)...
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