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Zinc Deficiency

Jill N. Tirabassi, MD Reviewed 06/2019
 


BASICS

DESCRIPTION

  • Nutritional condition whose manifestations may involve growth retardation, decreased bone mineralization, hypogonadism, cell-mediated immune dysfunction, poor wound healing, poor app...

DIAGNOSIS

HISTORY

  • Mild deficiency

    • Hypogeusia (decreased taste)

    • Dysosmia (altered smell sensation)

    • Decreased adaptation to dark

    • Oligospermia

    • Decreased serum testosterone level

    • Decreased lean body mass

    • Hypera...

TREATMENT

GENERAL MEASURES

Dietary diversification: increased animal proteins in diet, decreased phytates; diet fortification 

MEDICATION

  • Zinc supplements: Take at least 1 hour before or 2 hours after me...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Full activity 

Patient Monitoring

  • In patients receiving parenteral nutrition, obtain zinc at baseline and every 2 to 4 weeks. If dose is changed, measure 1 to 2 wee...

REFERENCES

1
Prasad AS. Discovery of human zinc deficiency: its impact on human health and disease. Adv Nutr.  2013;4(2):176–190. [View Abstract on OvidMedline]
2
Roohani N, Hurrell R, Kelishadi R, ...

ADDITIONAL READING

  • Wessells KR, King JC, Brown KH. Development of a plasma zinc concentration cutoff to identify individuals with severe zinc deficiency based on results from adults undergoing experim...

SEE ALSO

Alcohol Abuse and Dependence; Anemia, Sickle Cell; Failure to Thrive 

CODES

ICD10

  • E60 Dietary zinc deficiency

  • E83.2 Disorders of zinc metabolism

ICD9

269.3 Mineral deficiency, not elsewhere classified 

SNOMED

  • 238124008 zinc deficiency (disorder)

  • 190661004 Dietary zinc deficien...

CLINICAL PEARLS

  • Zinc deficiency is uncommon in the United States.

  • Elderly persons may have diets deficient in zinc.

  • Zinc deficiency may cause poor wound healing; consider supplementation when treating c...

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