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Anemia of Chronic Disease (Anemia of Inflammation), Pediatric

Kandace L. Gollomp, MD and Michele Puszkarczuk Lambert, MD, MSTR Reviewed 10/2018
 


BASICS

DESCRIPTION

  • Anemia that accompanies a variety of systemic diseases, with the common features of chronicity and inflammation

  • Anemia of chronic disease is more properly called anemia of inflammatio...

DIAGNOSIS

Signs and symptoms 
  • Various abnormal physical findings may be present, depending on the underlying chronic disease process.

  • May have mild pallor but will not have signs of circulatory collapse

  • ...

TREATMENT

GENERAL MEASURES

  • Iron

    • Generally, no role for iron therapy unless there is coexisting iron deficiency anemia.

    • However, recent studies in patients with renal disease have shown improved response ...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Patient Monitoring

Treatment of underlying disease process may promote slow resolution of associated anemia. Hematocrit increases ~6 to 8 weeks after start of reco...

ADDITIONAL READING

  • Cullis J. Anaemia of chronic disease. Clin Med (Lond).  2013;13(2):193–196. [View Abstract on OvidInsights]

  • Fraenkel PG. Anemia of Inflammation: a review. Med Clin North Am. ...

CODES

ICD9

  • 285.29 Anemia of other chronic disease

  • 285.21 Anemia in chronic kidney disease

  • 285.22 Anemia in neoplastic disease

  • 282.9 Hereditary hemolytic anemia, unspecified

  • 446.2 Hypersensitivity angiitis,...

FAQ

  • Q: Does anemia that is associated with a chronic disease require further evaluation?

  • A: If the anemia fits within the usual expectations for the patient’s diagnosis, there is no need to pursue furt...

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