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Aspergillosis, Pediatric

Rebecca Schein, MD Reviewed 10/2018
 


BASICS

DESCRIPTION

Aspergillosis is an infection caused by species of the mold Aspergillus. Invasive, allergic or chronic (saprophytic) disease occurs based on the immune status of the host. 
  • Invasive d...

DIAGNOSIS

HISTORY

  • Pulmonary and invasive disease typically presents with a high fever, dry cough, and chest pain. Shortness of breath and hemoptysis can occur.

  • Sinusitis causes facial pain or swelling, ...

TREATMENT

GENERAL MEASURES

  • Pediatric patients with prolonged neutropenia at risk for invasive aspergillosis should receive prophylaxis with voriconazole or micafungin. Posaconazole, which is approved f...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Patient Monitoring

  • Pulmonary aspergillosis should have a repeat chest CT scan 2 weeks into therapy to assess the response to treatment.

  • Other follow-up imaging shou...

ADDITIONAL READING

  • Burgos A, Zaoutis TE, Dvorak CC, et al. Pediatric invasive aspergillosis: a multicenter retrospective analysis of 139 contemporary cases. Pediatrics.  2008; 121(5):e1286–e1294....

CODES

ICD9

  • 117.3 Aspergillosis

  • 484.6 Pneumonia in aspergillosis

  • 518.6 Allergic bronchopulmonary aspergillosis

  • 380.15 Chronic mycotic otitis externa

  • 495.9 Unspecified allergic alveolitis and pneumonitis

ICD10

FAQ

  • Q: Does Aspergillus grown a respiratory culture from a healthy child require treatment?

  • A: No. Aspergillus is common in the environment and colonization may occur. Healthy, asymptomatic children do...

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