An acute illness caused by neurotoxins produced by Clostridium botulinum or related neurotoxigenic species, which results in cranial nerve palsies and a symmetric, descending, flacci...
IB
Symptoms include constipation, poor feeding/poor latch, diminished facial expression, droopy eyelids, difficulty swallowing, and generalized weakness.
Fever is typically absent (barr...
Patients with suspected botulism should be hospitalized and have continuous monitoring of heart rate, respiratory rate, and oxygenation, as well as frequent assessment of res...
IB has an estimated mortality rate of <1% in hospitalized patients. Complete recovery can be expected when the disease is recognized early and treated appropriately.
The mortal...
Arnon SS, Schechter R, Maslanka SE, et al. Human botulism immune globulin for the treatment of infant botulism. N Engl J Med. 2006;354(5):462–471. [View Abstract on OvidInsigh...
005.1 Botulism food poisoning
040.41 Infant botulism
040.42 Wound botulism
A05.1 Botulism food poisoning
A48.51 Infant botulism
A48.52 Wound botulism
398565003 Infection due to clostrid...
Q: Can IB recur?
A: True recurrence of IB has not been documented.
Q: Should antitoxin be given to persons who have ingested food that they think might be contaminated with botulinum toxin (foodborn...
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Clostridial diseases. Clostridia in the vegetative form inhabit the gastrointestinal tract of humans and animals. Spores pass in the feces, contaminate soil and plant materials, and are ingested or enter sites of penetrating wounds. Under anaerobic conditions they revert to vegetative forms. Plasmids in the vegetative forms elaborate toxins that cause several clostridial diseases. Food poisoning and necrotizing enteritis. Meat dishes left to cool at room temperature grow large numbers of cl...
Clostridial diseases. Clostridia in the vegetative form inhabit the gastrointestinal tract of humans and animals. Spores pass in the feces...