Celiac disease (CD) is a systemic immune-mediated disorder caused by a permanent sensitivity to gluten in genetically susceptible individuals.
“Gluten”
The collective term for specific...
The range of signs and symptoms secondary to CD is broad. Malabsorptive symptoms such as diarrhea and weight loss are more commonly seen in early childhood. Other more subtle gastrointestina...
Current treatment of CD consists of a strict, lifelong GFD.
Elimination of all wheat, rye, and barley is essential, with close care to avoid cross-contamination during the preparation and ser...
Close clinical monitoring of patients with newly diagnosed CD is important. Patients should be seen several times within the 1st year of diagnos...
Fasano A, Catassi C. Clinical practice. Celiac disease. N Engl J Med. 2012;367(25):2419–2426. [View Abstract on OvidInsights]
Hill ID, Dirks M, Liptak G, et al. Guideline for t...
396331005 Celiac disease (disorder)
197478000 Congenital celiac disease (disorder)
Q: Is biopsy confirmation necessary if my patient is already doing better on a GFD?
A: Yes. Referral to a pediatric gastroenterologist who can obtain small bowel biopsy is recommended in almost all...
Sign up for a 10-day FREE Trial now and receive full access to all content.
Villous atrophy with a flat surface, elongation of the crypts, and chronic inflammation of the lamina propria are characteristic of long-standing disease.
Villous atrophy with a flat surface, elongation of the crypts, and chronic inflammation of the lamina propria are characteristic of long-s...
A higher-power view shows damaged, cuboidal surface epithelium with numerous intraepithelial lymphocytes. The lamina propria is heavily infiltrated by plasma cells.
A higher-power view shows damaged, cuboidal surface epithelium with numerous intraepithelial lymphocytes. The lamina propria is heavily in...
<bold>Figure 37.3</bold> A child with celiac disease. Notice the protruding abdomen and wasted buttocks.