Characterized by growth deceleration, truncal obesity, characteristic skin chan...
The most common presenting symptom of the syndrome in childhood is weight gain accompanied by poor linear growth.
Additional pertinent features in the history of presenting illness oft...
The treatment of choice for Cushing disease is transsphenoidal surgery (TSS).
In most specialized centers with experienced neurosurgeons, the success rate of the first TSS is close to, or eve...
Following TSS in Cushing disease, patients will be transiently adrenally insufficient while the hypothalamic-pituitary-adrenal axis is recovering.
Stress doses of cortisol are necessary in...
Batista DL, Riar J, Keil M, et al. Diagnostic tests for children who are referred for the investigation of Cushing syndrome. Pediatrics. 2007;120(3):e575–e586. [View Abstract ...
E24.9 Cushing’s syndrome, unspecified
E24.0 Pituitary-dependent Cushing’s disease
E24.2 Drug-induced Cushing’s syndrome
E24.3 Ectopic ACTH syndrome
E24.8 Other Cush...
Q: What clinical clue is most useful to determine which children have obesity alone versus those with Cushing syndrome?
A: Cushing syndrome is associated with growth failure, whereas obesity is ass...
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A Female with Cushing's Syndrome
<bold>Fig GU 36-1. Cushing's syndrome</bold> due to functioning cortical adenoma. A 4-cm mass in the left adrenal gland (arrows) is seen posterior to the tail of the pancreas and anterior to the kidney (K). The arrowhead points to the normal right adrenal gland.<sup>29</sup>
<bold>Fig GU 36-1. Cushing's syndrome</bold> due to functioning cortical adenoma. A 4-cm mass in the left adrenal gland (arrow...
<bold><italic>Figure 18-19</bold> Cushing syndrome. A,</bold> Cushingoid obesity, including "buffalo hump" of dorsal fat. <bold>B,</bold> Cushingoid moon facies.
<bold><italic>Figure 18-19</bold> Cushing syndrome. A,</bold> Cushingoid obesity, including "buffalo hump" of dors...