A febrile illness (38.3°C on multiple occasions)
Present for >14 days
No apparent source despite careful history taking, physical exam, and pre...
Phase 1
Document fever.
Thorough history and physical exam
Determine whether constitutional symptoms (e.g., growth failure, developmental arrest) suggest a serious under...
Most children with FUO who lack a specific diagnosis fare well with resolution of fever and few or no recurrent episodes.
Occasionally, evoluti...
Chow A, Robinson JL. Fever of unknown origin in children: a systematic review. World J Pediatr. 2011;7(1):5–10. [View Abstract on OvidInsights]
Chusid MJ. Fever of unknown orig...
Q: Do all of the mentioned tests need to be performed?
A: A “shotgun” approach to testing is rarely useful in making the diagnosis, and unanticipated abnormalities (e.g., false-positives) may lead ...
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