Many (50–75%) infected individuals are asymptomatic.
Clinical presentation (acute):
Sudden-onset watery, foul-smelling diarrhea without blood/pus/mucus
Malaise
Bloating/flatulence
Steatorrhea
Abdo...
Metronidazole (not indication approved by FDA)
15 mg/kg/24 h divided t.i.d. PO for 5 to 10 days
Efficacy 80–100%
Poor palatability
Tinidazole (approved for children ≥3 years)
50 mg/kg, ...
Symptom recurrence can be attributable to reinfection, secondary lactose intolerance, insufficient treatment, or drug resistance.
Detailed exposu...
Ali SA, Hill DR. Giardia intestinalis. Curr Opin Infect Dis. 2003;16(5):453–460. [View Abstract on OvidInsights]
American Academy of Pediatrics. Giardia intestinalis (formerly ...
007.1 Giardiasis
A07.1 Giardiasis [lambliasis]
58265007 Giardiasis (disorder)
10679007 Infection by Giardia lamblia
Q: How is G. intestinalis likely contracted?
A: Direct person-to-person contact via fecal–oral transmission. Most community-wide epidemics occur from a contaminated water supply (drinking water), a...
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<bold>FIGURE 53-3</bold> <bold>Scanning electron micrograph of <i>Giardia lamblia.</i> A.</bold> <i>G. lamblia</i> adhering to the gastrointestinal epithelium using its ventral sucking disk. Patients with giardiasis may have a significant reduction in the amount of absorptive surface available because of the large number of adhering parasites. <bold>B.</bold> On detaching from the intestinal epithelium, the organisms often leave a clear impression...
<bold>FIGURE 53-3</bold> <bold>Scanning electron micrograph of <i>Giardia lamblia.</i> A.</bold> <...
<bold>Fig GI 26-2 Giardiasis.</bold> Irregular fold thickening is most prominent in the proximal small bowel.