Henoch-Schönlein purpura (HSP), also called immunoglobulin A vasculitis, is an immunologically mediated, purpuric, nonthrombocytopenic, and systemic vasculitis involving the small bl...
Onset is often acute, appearing over several days to weeks.
Recent history of illness especially URI or streptococcal infection
Purpuric rash and joint pain are usually the presenting s...
HSP is generally self-limiting with supportive care including adequate oral hydration.
Pain control with analgesics like acetaminophen
Typically, NSAIDs should be avoided to prevent ...
Majority of patients who progress to renal involvement evolve in the first 2 months.
Urinalysis and blood pressure and monitoring:
Weekly or biwee...
Gedalia A, Cuchacovich R. Systemic vasculitis in childhood. Curr Rheumatol Rep. 2009;11(6):402–409. [View Abstract on OvidInsights]
Jauhola O, Ronkainen J, Koskimies O, et al. ...
Q: When will the rash disappear?
A: The rash may appear uncomfortable. It is generally painless and nonpruritic. Patient should have complete resolution in 4 to 6 weeks.
Q: When should a patient wit...
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<bold>FIG. 86.4.</bold> AC: Henoch-Schönlein purpura (HSP). Skin lesions noted on the lower extremity and abdomen of a 16-year-old boy with biopsy-proven HSP; immunoglobulin A deposits were noted on biopsy. (Courtesy of Dr. Sate Hazma, dermatopathology fellow, University of Birmingham, and Dr. Amy Theos, Assistant Professor, Department of Dermatology, University of Alabama at Birmingham.)
<bold>FIG. 86.4.</bold> AC: Henoch-Schönlein purpura (HSP). Skin lesions noted on the lower extremity and abdomen of a 16-yea...
<bold>FIG. 86.4.</bold> AC: Henoch-Schönlein purpura (HSP). Skin lesions noted on the lower extremity and abdomen of a 16-year-old boy with biopsy-proven HSP; immunoglobulin A deposits were noted on biopsy.
<bold>Fig GU 7-3. Henoch-Schönlein purpura.</bold> Hemorrhage and edema in the intestinal wall cause regular thickening of small bowel folds.
<bold>Fig GU 7-3. Henoch-Schönlein purpura.</bold> Hemorrhage and edema in the intestinal wall cause regular thickening of sma...