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Hepatomegaly, Pediatric

Sivan Kinberg, MD, MS, MA and Sarah S. Lusman, MD, PhD Reviewed 10/2018
 


BASICS

DESCRIPTION

Hepatomegaly is enlargement of the liver beyond age-adjusted normal values. It can be due to intrinsic liver disease or associated with systemic diseases seen in infants and children...

DIAGNOSIS

HISTORY

Obtain a detailed history to identify potential risk factors for liver disease and to evaluate for underlying systemic disease. 
  • Question: Prenatal history suggesting possible congenit...

TREATMENT

Depends on underlying etiology of hepatomegaly 
ALERT

Refer to gastroenterologist or hepatologist if

  • Unexplained or persistent elevation of liver enzymes

  • Decreased synthetic function or signs of...

ADDITIONAL READING

  • Clayton PT. Diagnosis of inherited disorders of liver metabolism. J Inherit Metab Dis.  2003;26(2–3):135–146. [View Abstract on OvidInsights]

  • Clemente M, Schwarz K. Hepatitis: g...

CODES

ICD9

  • 789.1 Hepatomegaly

  • 070.9 Unspecified viral hepatitis without mention of hepatic coma

  • 573.0 Chronic passive congestion of liver

  • 576.2 Obstruction of bile duct

ICD10

  • R16.0 Hepatomegaly, not elsewhe...

FAQ

  • Q: Why does cholestasis cause pruritus?

  • A: This phenomenon probably reflects an abnormal accumulation of bile acids in the skin.

  • Q: Do patients with chronic liver disease have any different nutritio...

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