A disorder of the humoral immune system characterized by deficient or absent immunoglobulins and the inability to produce specific antibody
Subtypes include primary immunodeficiency a...
Recurrent upper and lower respiratory tract infections (otitis media, pneumonia, and sinusitis)
Infections with encapsulated bacteria such as Streptococcus pneumoniae, Haemophilus infl...
Appropriate antimicrobial therapy at first sign of infection. Prompt initiation of therapy is recommended.
Select patients may benefit from prophylactic antibiotics.
Regular replacem...
Conley ME. Genetics of hypogammaglobulinemia: what do we really know? Curr Opin Immunol. 2009;21(5):466–471. [View Abstract on OvidInsights]
Jolles S. The variable in common va...
279.00 Hypogammaglobulinemia, unspecified
279.04 Congenital hypogammaglobulinemia
279.01 Selective IgA immunodeficiency
279.02 Selective IgM immunodeficiency
279.03 Other selective immunoglobuli...
Q: When should I check immunoglobulin levels?
A: Immunoglobulins and antibody responses to vaccinations may be considered in any patient with a history of recurrent sinopulmonary infections.
Q: I ha...
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