Increased susceptibility to infection
Serum IgA <7 mg/dL and a norma...
Patients with IgA deficiency
Can have recurrent sinopulmonary infections
Can have frequent GI infections
Tend to have atopic disease such as allergic rhinitis, allergic conjunctivitis, u...
There is no specific drug therapy.
Recurrent infections should be treated aggressively with broad-spectrum antibiotics.
Antibiotic prophylaxis to prevent recurrent sinopulmonar...
Patients should be observed for the following:
Sinopulmonary infections, particularly signs/symptoms of bronchiectasis
Burrows PD, Cooper MD. IgA deficiency. Adv Immunol. 1997;65:245–276. [View Abstract on OvidInsights]
Janzi M, Kull I, Sjöberg R, et al. Selective IgA deficiency in early life: ...
Q: Should patients with IgA deficiency be monitored for the development of progressive immunodeficiency?
A: Patients with IgA deficiency should be monitored for progression to CVID, as this is asso...
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