Infantile spasms (IS) are seizures commonly associated with West syndrome—a severe infantile epileptic encephalopathy often with poor developmental outcome.
IS are characterized by su...
A description of spells including the timing of onset (single IS can precede clustering)
Prenatal and perinatal history including complications of pregnancy or delivery, gestational an...
Generally accepted 1st-line medical treatments include adrenocorticotropic hormone (ACTH), high-dose oral corticosteroids (HOC), and vigabatrin.
The etiology may determine...
Prognosis depends on the underlying etiology and associated conditions.
The best prognosis is typically for those with unknown etiology and normal development before diagnosis.
Abo...
Baram TZ, Mitchell WG, Tournay A, et al. High-dose corticotropin (ACTH) versus prednisone for infantile spasms: a prospective, randomized, blinded study. Pediatrics. 1996;97(3...
345.60 Infantile spasms, without mention of intractable epilepsy
345.61 Infantile spasms, with intractable epilepsy
G40.822 Epileptic spasms, not intractable, w/o status epilepticus
G40.82...
Q: Should I prescribe an abortive medication for longer clusters of IS?
A: Generally, No. IS do not typically respond acutely to benzodiazepines.
Q: My patient has IS and an abnormal EEG but no hyps...
Sign up for a 10-day FREE Trial now and receive full access to all content.