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Kawasaki Disease, Pediatric

Rebecca Reindel, MD and Stanford T. Shulman, MD Reviewed 10/2018
 


BASICS

DESCRIPTION

  • Kawasaki disease (KD) is a medium-sized vessel arteritis of early childhood with a predilection for the coronary arteries, which can result in dilatation, aneurysms, thrombosis, and ...

DIAGNOSIS

  • KD is a clinical diagnosis.

  • Current diagnostic criteria: fever for ≥5 days and ≥4 of 5 clinical findings, which need not be present at the same time

    • Extremity changes (erythema of palms, soles...

TREATMENT

GENERAL MEASURES

  • Rapid diagnosis and treatment can decrease the risk of coronary artery aneurysms.

  • Close follow-up and monitoring for the development of aneurysms after discharge

MEDICATION

  • Comb...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

  • Low-dose aspirin should be continued until follow-up ECHO at 2 weeks and 6 to 8 weeks after discharge are normal.

  • Some centers perform ECHO at 6 to 12 months after...

ADDITIONAL READING

  • Burns JC, Glodé MP. Kawasaki syndrome. Lancet.  2004;364(9433):533–544. [View Abstract on OvidInsights]

  • Freeman AF, Shulman ST. Refractory Kawasaki disease. Pediatr Infect Dis J...

CODES

ICD9

446.1 Acute febrile mucocutaneous lymph node syndrome [MCLS] 

ICD10

M30.3 Mucocutaneous lymph node syndrome [Kawasaki] 

SNOMED

75053002 Acute febrile mucocutaneous lymph node syndrome (disorder)...

FAQ

  • Q: Who first described KD?

  • A: Tomisaku Kawasaki, MD is a pediatrician and graduate of the Chiba University School of Medicine. He noted his first case of the disease while working in the Department...

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