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Lupus Erythematosus, Pediatric

Elizabeth Candell Chalom, MD Reviewed 10/2018
 


BASICS

DESCRIPTION

Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease characterized by production of antibodies to various components of the cell nucleus and tissues, in conjunction...

DIAGNOSIS

  • Classification criteria are used for research purposes but when met, have high sensitivity and specificity for diagnosis of lupus.

  • 4 of the following 11 criteria, developed by the American Co...

TREATMENT

GENERAL MEASURES

Avoid excessive sun exposure and use sunscreen liberally. 

MEDICATION

  • NSAIDs

    • May be used for musculoskeletal and mild systemic complaints, although ibuprofen has been noted to c...

ONGOING CARE

PROGNOSIS

  • Extremely variable. Renal disease and CNS involvement are poor prognostic signs, whereas systemic complaints and joint findings are not.

  • 10-year survival in children presenting wi...

ADDITIONAL READING

  • Brunner HI, Huggins J, Klein-Gitelman MS. Pediatric SLE—towards a comprehensive management plan. Nat Rev Rheumatol.  2011;7(4):225–233. [View Abstract on OvidInsights]

  • Gottlieb ...

CODES

ICD9

  • 695.4 Lupus erythematosus

  • 710.0 Systemic lupus erythematosus

ICD10

  • L93.0 Discoid lupus erythematosus

  • M32.9 Systemic lupus erythematosus, unspecified

  • L93.2 Other local lupus erythematosus

  • M32.10 Sy...

FAQ

  • Q: If a patient has a positive ANA but no clinical signs of SLE, how often should the ANA be followed?

  • A: A positive ANA test will usually remain positive indefinitely, but it has no real significa...

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