Lymphadenopathy, Pediatric

Term used to describe ≥1 enlarged lymph nodes >10 mm in diameter (for inguinal nodes, >15 mm; for epitrochlear nodes, >5 mm)

Any palpable supraclavicular and popliteal lymph ...

Preceding symptoms (e.g., URI symptoms preceding cervical lymphadenopathy)

Localizing signs or symptoms (e.g., stomatitis may be associated with submandibular lymphadenopathy)

Duration

• A...

Treat underlying disease.

Close observation, unless history and physical suggest malignancy or lymphadenitis

Localized lymphadenopathy: Observe for several weeks or treat with antibiotics if indicated.

Serial observation if nodes are persistently enlarge...

Albright JT, Pransky SM. Nontuberculous mycobacterial infections of the head and neck. Pediatr Clin North Am.  2003;50(2):503–514. [View Abstract on OvidInsights]

Bamji M, Stone...

785.6 Enlargement of lymph nodes

130.7 Toxoplasmosis of other specified sites

771.2 Other congenital infections specific to the perinatal period

289.3 Lymphadenitis, unspecified, except mesente...

Q: When should there be concern about malignancy in a child with lymphadenopathy?

A: Malignancy should be considered in any child who has lymphadenopathy that does not improve in spite of antibioti...