Macrocytosis refers to a blood condition in which red blood cells (RBCs) are larger than normal. It is reported in terms of mean corpuscular volume (MCV). Normal MCV values range fro...
Pallor, fatigue, poor appetite, irritability caused by anemia
Malabsorption/diarrhea, steatorrhea, weight loss can be signs of gastrointestinal (GI) acute infections or chronic inflamm...
It is imperative that vitamin B12 deficiency is diagnosed correctly. Treatment of undiagnosed vitamin B12 deficiency with folate replacement will not improve the neurologic deficits and...
Aslinia F, Mazza JJ, Yale SH. Megaloblastic anemia and other causes of macrocytosis. Clin Med Res. 2006;4(3):236–241. [View Abstract on OvidInsights]
Kaferle J, Strzoda CE. Eva...
281.3 Other specified megaloblastic anemias not elsewhere classified
289.89 Other specified diseases of blood and blood-forming organs
281.2 Folate-deficiency anemia
D53.1 Other megaloblas...
Q: What are the common dietary sources of vitamin B12?
A: Red meat, liver, seafood, chicken, dairy products, eggs
Q: What are the common dietary sources of folate?
A: Vegetables (especially green, le...
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FIGURE 41.7. The peripheral blood smear of refractory anemia with ringed sideroblasts is characterized by a dimorphic red cell population. A distinct population of hypochromic, often microcytic erythrocytes can be found admixed with normochromic, normocytic, or macrocytic erythrocytes.
FIGURE 41.7. The peripheral blood smear of refractory anemia with ringed sideroblasts is characterized by a dimorphic red cell population....
Iron Deficiency Anemia (IDA) White cells Not remarkable Platelets Normal or slightly increased Red cells Hb and Hct decreased Microcytic, hypochromic anemia Reticulocytes normal or slightly increased Increased RDW Pencil or cigar shaped red cells, codocytes Bone marrow Normoblastic hyperplasia Absent hemosiderin Decreased sideroblasts (less than 10%) Normoblasts are smaller than normal with ragged rims of cytoplasm containing little h...
Iron Deficiency Anemia (IDA) White cells Not remarkable Platelets Normal or slightly increased Red cells Hb and Hct decrease...
Microangiopathic Hemolytic Anemia White cells Not remarkable Platelets Decreased Red cells Normocytic, normochromic anemia Increased reticulocytes Schistocytes Polychromatophilia Peripheral Smear
Microangiopathic Hemolytic Anemia White cells Not remarkable Platelets Decreased Red cells Normocytic, normochromic anemia ...