Neonatal cholestasis is defined as elevated conjugated bilirubin levels that occur in the newborn period and often extends during the infancy. It typically indicates hepatobiliary dy...
Pregnancy and birth history
History of consanguinity
Family history/racial background
Infectious exposure
TPN exposure, prolonged history of NPO status
Presence/absence of extrahepatic man...
Ursodeoxycholic acid (improvement in hepatic function and absorption of fat-soluble vitamins)
Cholic or chenodeoxycholic acid for BASD
Antihistamines (for pruritus associated with ch...
Nutritional support needed. Typically, an elemental formula with high content medium-chain triglycerides is better absorbed in cholestasis.
Consider need for nasogastric tube feeds.
Spe...
Bakshi B, Sutcliffe A, Akindolie M, et al. How reliably can paediatric professionals identify pale stool from cholestatic newborns? Arch Dis Child Fetal Neonatal Ed. 2012;97(5...
576.8 Other specified disorders of biliary tract
751.61 Biliary atresia
774.4 Perinatal jaundice due to hepatocellular damage
273.4 Alpha-1-antitrypsin deficiency
K83.1 Obstruction of bile ...
Q: What information in the patient’s history can be used to identify neonatal cholestasis?
A: Direct observation of urine color along with stool color, as acholic stools and dark urine suggest the ...
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