Neurofibromatosis-1, Pediatric

FIG. 6.27. A, B: This boy has the characteristic large cafe-au-lait lesions of neurofibromatosis.

FIG. 6.27. A, B: This boy has the characteristic large cafe-au-lait lesions of neurofibromatosis.

FIGURE 12.2. Neurofibromatosis. Posterior view demonstrating various types of cutaneous tumors. These include the pedunculated molluscum fibrosum and subcutaneous neurofibromas. Note the area of hyperpigmentation of the right elbow and a typical café au lait lesion. (Courtesy of Dr. V. M. Riccardi, Neurofibromatosis Institute, La Crescenta, CA.)

FIG. 7.6. Neurofibromatosis. Discrete, hyperpigmented macules (arrows), referred to as cafe-au-lait spots, are visible on the backs of the legs of a patient with neurofibromatosis. (From Becker KL, Bilezikian JP, Brenner WJ, et al. Principles and practice of endocrinology and metabolism, 3rd ed. Philadelphia: Lippincott Williams & Wilkins, 2001:1999, with permission.)

<bold>Fig SK 13-2. Neurofibromatosis.</bold> Bilateral acoustic neuromas (A) in a young girl with progressive bilateral sensorineural hearing loss.

<bold>Fig SK 24-14. Neurofibromatosis</bold> with hamartoma (arrows).

Figure 11-413 <bold>NEUROFIBROMATOSIS: FOOT.</bold> Observe the thin, irregular, scalloped appearance of the metatarsal bones. This deformity in the metatarsal bones is likened to the twisted ribbon appearance seen affecting the ribs in neurofibromatosis. Mesodermal dysplasia is the underlying pathologic process allowing this radiographic appearance to occur in neurofibromatosis.

Figure 11-414 <bold>NEUROFIBROMATOSIS: DEFORMITY.</bold> Observe the bowing deformity of the tibia, with alteration of the bony texture as a result of the underlying changes of neurofibromatosis. (Courtesy of C.H. Quay, MD, Melbourne,Australia.)

Neurofibromatosis type I - multiple neurofibromas

A large caf?u-lait macule in a patient with neurofibromatosis