Skip to main content

Parvovirus B19 (Erythema Infectiosum, Fifth Disease), Pediatric

Camille Sabella, MD Reviewed 10/2018
 


BASICS

DESCRIPTION

Parvovirus B19 (B19) is a small, single-stranded DNA virus of the family Parvoviridae. There are three major genetic variants (1 to 3). B19 is a common infection in humans, most ofte...

DIAGNOSIS

Diagnosis depends on recognition of typical symptoms and the results of laboratory testing. 

HISTORY

  • Erythema infectiosum (fifth disease)

    • Characterized by an erythematous facial rash with a dis...

TREATMENT

GENERAL MEASURES

  • There is no specific antiviral therapy for B19 infection.

  • Most patients require supportive care only.

  • Transfusions may be required for treatment of severe anemia in patients wi...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Expected course of illness 
  • The rash of erythema infectiosum in a child or adult may last up to 20 days. It may, at times, fade and/or intensify, depending on sunl...

ADDITIONAL READING

  • American Academy of Pediatrics. Parvovirus B19. In: Kimberlin DW, Brady MT, Jackson MA, et al, eds. Red Book®: 2015 Report of the Committee on Infectious Diseases. Elk Grove Villag...

CODES

ICD9

057.0 Erythema infectiosum (fifth disease) 

ICD10

B08.3 Erythema infectiosum [fifth disease] 

SNOMED

34730008 erythema infectiosum (disorder) 

FAQ

  • Q: When may children with B19 infection return to school?

  • A: Children are contagious only during the prodromal phase of illness, which is often unrecognized. Once the rash appears, they are no long...

Subscribe to Access Full Content

Sign Up for a 10-Day Free Trial

Sign up for a 10-day FREE Trial now and receive full access to all content.

 
×