Persistent constitutional symptoms
Bilateral calf pain and other myalgia
Abdominal pain
Weight loss
Unexplained fever
Headache
Arthralgia
Rashes
Seizures
Weakness
Check skin for th...
Ideally, diagnosis established with angiography or biopsy before beginning treatment
Corticosteroids are mainstay.
Usually start at dose of oral prednisone 1 to 2 mg/kg/24 h and adju...
Watch for the following:
Rising creatinine and BUN levels
Severe abdominal pain suggests peritoneal bleed.
Chest pain or cardiac dysf...
Eleftheriou D, Dillon MJ, Tullus K, et al. Systemic polyarteritis nodosa in the young: a single-center experience over thirty-two years. Arthritis Rheum. 2013;65(9):2476–2485....
155441006 Polyarteritis nodosa (disorder)
239926000 Cutaneous polyarteritis nodosa
239925001 Polyarteritis nodosa with single o...
Q: When should I consider polyarteritis nodosa in the differential?
A: There are five major clues to polyarteritis nodosa: (i) prolonged constitutional symptoms without a diagnosis, (ii) multisyste...
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<bold>Fig GU 7-2 Polyarteritis nodosa.</bold> An aortogram demonstrates innumerable small aneurysms arising from vessels throughout the abdomen. The aorta and its major branches are spared.
<bold>Fig GU 7-2 Polyarteritis nodosa.</bold> An aortogram demonstrates innumerable small aneurysms arising from vessels throu...
Nodular, painful, hemorrhagic skin lesion in a patient with polyarteritis nodosa.
Polyarteritis nodosa. The intense inflammatory cell infiltrate in the arterial wall and surrounding connective tissue is associated with fibrinoid necrosis and disruption of the vessel wall.
Polyarteritis nodosa. The intense inflammatory cell infiltrate in the arterial wall and surrounding connective tissue is associated with f...
Areas of conjunctival edema and necrosis in polyarteritis nodosa.