Appearance of pubic hair before age 8 years in girls and age 9 years in boys with elevated adrenal androgens (dehydroepiandrosterone [DHEA] or dehydroepiandrosterone-sulfate [DHEA-S]...
Careful attention to presence of any other signs of sexual precocity, as well as rate of progression
Family history of pubertal development, infertility, irregular menses, hirsutism, p...
No treatment
Reassure parents and children that this is a benign process.
Reassess every 6 months to look for signs of virilization and/or pubertal progression.
Regression does not occur.
Increasing virilization suggests nonclassical congenital adrenal hyperplasia or early PCOS.
Watch for other signs of puberty, such as breast development, testicul...
Auchus RJ, Rainey WE. Adrenarche—physiology, biochemistry and human disease. Clin Endocrinol (Oxf). 2004;60(3):288–296. [View Abstract on OvidInsights]
Herman-Giddens ME, Slora...
Q: Is there a dietary cause of excess adrenal hormones?
A: No.
Q: Does premature adrenarche mean puberty will be early?
A: The onset of puberty in these children is within the normal range and should...
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