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Premature Thelarche, Pediatric

Patricia Vuguin, MD, MSc Reviewed 10/2018
 


BASICS

DESCRIPTION

  • Breast development in girls <8 years of age without evidence of sexual hair development, vaginal mucosa estrogenization, linear growth acceleration, rapid bone maturation, adult b...

DIAGNOSIS

HISTORY

  • Careful assessment of onset and progression of breast tissue

  • Careful assessment of growth (growth velocity changes in height percentiles)

  • Family history of early puberty and or early me...

TREATMENT

GENERAL MEASURES

  • Observation

  • Reassurance for benign processes

ONGOING CARE

  • Regression often occurs by 2 years but may occur up to 6 years after onset.

  • No specific characteristics assist with prediction of which girls with premature thelarche will go on to have pr...

ADDITIONAL READING

  • Diamantopoulos S, Bao Y. Gynecomastia and premature thelarche: a guide for practitioners. Pediatr Rev.  2007;28(9):e57–e68. [View Abstract on OvidInsights]

  • Haber HP, Wollmann HA...

CODES

ICD9

259.1 Precocious sexual development and puberty, not elsewhere classified 

ICD10

E30.8 Other disorders of puberty 

SNOMED

102889008 Premature development of the breasts (finding) 

FAQ

  • Q: Does premature thelarche predispose the child to later abnormalities in pubertal development?

  • A: If onset occurs after age 2 years, the girl may be more likely to enter puberty earlier. However,...

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