Breast development in girls <8 years of age without evidence of sexual hair development, vaginal mucosa estrogenization, linear growth acceleration, rapid bone maturation, adult b...
Careful assessment of onset and progression of breast tissue
Careful assessment of growth (growth velocity changes in height percentiles)
Family history of early puberty and or early me...
Observation
Reassurance for benign processes
Regression often occurs by 2 years but may occur up to 6 years after onset.
No specific characteristics assist with prediction of which girls with premature thelarche will go on to have pr...
Diamantopoulos S, Bao Y. Gynecomastia and premature thelarche: a guide for practitioners. Pediatr Rev. 2007;28(9):e57–e68. [View Abstract on OvidInsights]
Haber HP, Wollmann HA...
Q: Does premature thelarche predispose the child to later abnormalities in pubertal development?
A: If onset occurs after age 2 years, the girl may be more likely to enter puberty earlier. However,...
Sign up for a 10-day FREE Trial now and receive full access to all content.