Reye syndrome is described as acute noninflammatory encephalopathy and fatty degeneration of the liver which may be idiopathic or secondary.
Reye syndrome is associated with aspirin (...
Typical history includes a viral illness with a remission period of 3 to 5 days followed by acute onset of vomiting and neurologic changes.
At least one episode prodromal illness was r...
Stabilization of airway, breathing, and circulation should always be priority.
Frequent assessment of neurologic status, especially signs of elevated ICP is required.
Admission to pediatric intensive care unit should be considered early in the disease course for close neurologic and cardiopulmonary monitoring.
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Altman LK. Tale of triumph on every aspirin bottle. The New York Times. May 11, 1999. [View Abstract on OvidInsights]
Belay ED, Bresee JS, Holman RC, et al. Reye’s syndrome in the Un...
Q: Is Reye syndrome fatal?
A: ~30% of children will die, usually due to cerebral edema. Mortality rates are best predicted by neurologic state at the onset of presentation.
Q: How can the neurologic...
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Microvesicular fatty liver. A liver biopsy specimen in a case of Reye syndrome shows small droplet fat in hepatocytes and centrally located nuclei.
Microvesicular fatty liver. A liver biopsy specimen in a case of Reye syndrome shows small droplet fat in hepatocytes and centrally locate...