A postinfectious inflammatory disease caused by rheumatogenic strains of group A β-hemolytic Streptococcus (GABHS)
Acute rheumatic fever (ARF) results in a wide range of disease, from...
Evidence of recent GABHS infection PLUS two major OR one major and two minor criteria for initial ARF; as above, OR t...
Anti-inflammatory
Aspirin 100 mg/kg/24 h PO divided q6–8h; may be reduced to 60 to 70 mg/kg/24 h when fever and acute-phase reactants have normalized for 6 to 8 weeks
Antib...
Patients without carditis
Close follow-up is needed for 2 to 3 weeks to assess patient’s condition for development of acute carditis.
Long-term pediatric follow-up ...
Cilliers A, Manyemba J, Adler AJ, et al. Anti-inflammatory treatment for carditis in acute rheumatic fever. Cochrane Database Syst Rev. 2012;(6): CD003176. [View Abstract on O...
390 Rheumatic fever without mention of heart involvement
398.90 Rheumatic heart disease, unspecified
714.0 Rheumatoid arthritis
391.9 Acute rheumatic heart disease, unspecified
I00 Rheumati...
Q: Does a negative throat culture rule out ARF?
A: No. Throat cultures may be negative in 2/3 of patients.
Q: Is there a vaccine available that is effective in preventing ARF?
A: Not at present. Give...
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<bold>FIG. 79.1.</bold> A: Mitral valve from a patient with mitral stenosis from rheumatic fever (viewed from atrium). Notice the thickened calcific leaflets and thickened chordae tendineae compared with a normal mitral valve (B). (Courtesy of W.D. Edwards, M.D., Mayo Clinic.)
<bold>FIG. 79.1.</bold> A: Mitral valve from a patient with mitral stenosis from rheumatic fever (viewed from atrium). Notice ...
<bold>FIG. 79.2.</bold> A: Erythema marginatum in an adult with rheumatic fever. B: Closer view of rash. (Courtesy of P. Witman, M.D., Mayo Clinic.)
<bold>FIG. 79.2.</bold> A: Erythema marginatum in an adult with rheumatic fever. B: Closer view of rash. (Courtesy of P. Witma...