EOS/Blau—patients have more typical clinical triad presentation; gene mutation testing can confirm diagnosis.
ATD—presentation is more vague; symptoms are less specific and biopsy confirmatio...
Pitfalls include overtreating asymptomatic lymphadenopathy and not detecting hypercalciuria.
Corticosteroids oft...
Referral to rheumatologist indicated
Regular ophthalmologic assessment
Signs to watch for:
Rising creatinine levels
Shortness of breath
Persistent uv...
Baumann RJ, Robertson WC Jr. Neurosarcoid presents differently in children than in adults. Pediatrics. 2003;112(6, Pt 1):e480–e486. [View Abstract on OvidInsights]
Blau EB. Fam...
135 Sarcoidosis
517.8 Lung involvement in other diseases classified elsewhere
713.7 Other general diseases with articular involvement
695.2 Erythema nodosum
D86.9 Sarcoidosis, unspecified
D8...
Q: Why is therapy in childhood sarcoidosis more aggressive compared with adults?
A: These may be two distinct granulomatous diseases. EOS/Blau is a very aggressive and destructive disease requiring...
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FIGURE 28.2. Radiographs illustrating the different stages of sarcoidosis. A: Stage I. Bilateral hilar adenopathy and paratracheal adenopathy with normal lung fields. B: Stage II. Bilateral hilar adenopathy with interstitial lung field involvement. C: Stage III. Lung field involvement only. D: Stage IV. Severely fibrotic lungs with volume loss and cyst formation.
FIGURE 28.2. Radiographs illustrating the different stages of sarcoidosis. A: Stage I. Bilateral hilar adenopathy and paratracheal adenopa...
Figure 5.62. Sarcoidosis-related retinal phlebitis with perivascular exudates known as "candle-wax drippings."
Schaumann body consists of fragmented irregular calcified basophilic refractile structure in the cytoplasm of a multinucleated giant cell in a sarcoidosis granuloma.
Schaumann body consists of fragmented irregular calcified basophilic refractile structure in the cytoplasm of a multinucleated giant cell ...