Diagnosis:
In the United States, diagnosed on newborn screening with hemoglobin electrophoresis showing FSA or FS findings
Often asymptomatic in early infancy (<6 months) due to prot...
Teaching regarding fever precautions (for functional asplenia in SCD patients), signs of acute chest, splenic sequestration monitoring, aplastic crises, stroke identification...
Adams RJ, Brambilla D; for Optimizing Primary Stroke Prevention in Sickle Cell Anemia (STOP 2) Trial Investigators. Discontinuing prophylactic transfusions used to prevent stroke in...
282.60 Sickle-cell disease, unspecified
282.5 Sickle-cell trait
282.41 Sickle-cell thalassemia without crisis
282.61 Hb-SS disease without crisis
D57.1 Sickle-cell disease without crisis
D57...
Q: When can I stop penicillin prophylaxis?
A: Most morbidity and mortality from infections in sickle cell anemia occur in the first 5 years of life. The risk of pneumococcal sepsis decreases with a...
Sign up for a 10-day FREE Trial now and receive full access to all content.
FIGURE 41.7. The peripheral blood smear of refractory anemia with ringed sideroblasts is characterized by a dimorphic red cell population. A distinct population of hypochromic, often microcytic erythrocytes can be found admixed with normochromic, normocytic, or macrocytic erythrocytes.
FIGURE 41.7. The peripheral blood smear of refractory anemia with ringed sideroblasts is characterized by a dimorphic red cell population....
FIGURE 10-7.Sickling of red blood cells in sickle cell anemia. (clumped) by anti-A serum; those in type B blood are agglutinated by anti-B serum. Type AB blood cells are agglutinated by both sera, and type O blood is not agglutinated by either serum.
FIGURE 10-7.Sickling of red blood cells in sickle cell anemia. (clumped) by anti-A serum; those in type B blood are agglutinated by anti-B...
Iron Deficiency Anemia (IDA) White cells Not remarkable Platelets Normal or slightly increased Red cells Hb and Hct decreased Microcytic, hypochromic anemia Reticulocytes normal or slightly increased Increased RDW Pencil or cigar shaped red cells, codocytes Bone marrow Normoblastic hyperplasia Absent hemosiderin Decreased sideroblasts (less than 10%) Normoblasts are smaller than normal with ragged rims of cytoplasm containing little h...
Iron Deficiency Anemia (IDA) White cells Not remarkable Platelets Normal or slightly increased Red cells Hb and Hct decrease...
Microangiopathic Hemolytic Anemia White cells Not remarkable Platelets Decreased Red cells Normocytic, normochromic anemia Increased reticulocytes Schistocytes Polychromatophilia Peripheral Smear
Microangiopathic Hemolytic Anemia White cells Not remarkable Platelets Decreased Red cells Normocytic, normochromic anemia ...
Sickle cell anemia. A peripheral blood smear shows numerous sickled cells, as well as normoblasts and occasional target cells. The erythrocyte to the left of center contains a Howell-Jolly body, indicative of functional hyposplenism.
Sickle cell anemia. A peripheral blood smear shows numerous sickled cells, as well as normoblasts and occasional target cells. The erythro...