Spinal muscular atrophy (SMA) is a progressive disorder of motor neurons in the spinal cord and brainstem.
Major symptom is proximal weakness.
Three forms are described based on clinic...
Hypotonia and weakness are the primary features. Infants with SMA I will be floppy and less active and have delayed motor milestones, with preserved language/social interaction (a bri...
An apparently minor respiratory infection may carry a higher risk of respiratory failure in SMA I and later stages of SMA II and III. Depending on family/patient wishes regarding respir...
Cure SMA: http://www.curesma.org
FightSMA: http://www.fightsma.org
Muscular Dystrophy Association: http://www.mda.org
SMA Foundation: http://www.smafoundation.org
Su...
Arnold WD, Burghes AH. Spinal muscular atrophy: development and implementation of potential treatments. Ann Neurol. 2013;74(3):348–362. [View Abstract on OvidInsights]
Chung BH...
335.10 Spinal muscular atrophy, unspecified
335.0 Werdnig-Hoffmann disease
335.11 Kugelberg-Welander disease
335.19 Other spinal muscular atrophy
G12.0 Infantile spinal muscular atrophy, ty...
Q: Can routine vaccinations be given to children with SMA?
A: Yes. In addition to routine vaccinations, yearly influenza and respiratory syncytial virus (RSV) vaccinations are recommended.
Q: How mu...
Sign up for a 10-day FREE Trial now and receive full access to all content.