Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe, potentially fatal, mucocutaneous reactions, typically caused by medications. Clinically, they are char...
Prodromal period for 1 to 7 days of low-grade fever, sore throat or upper respiratory infection or dysphagia, and general malaise; patient may also complain of pain or stinging in the...
Stop all potentially offending medications.
Early admission to burn unit or pediatric intensive care unit for initial stabilization and management of fluid, electrolytes, ...
Follow-up with a dermatologist and/or wound care specialist in addition to ophthalmologist
Reepithelialization often starts within days and may take up to 3 weeks ...
Bastuji-Garin S, Rzany B, Stern RS, et al. Clinical classification of cases of toxic epidermal necrolysis, Stevens-Johnson syndrome, and erythema multiforme. Arch Dermatol. 19...
695.13 Stevens-Johnson syndrome
695.14 Stevens-Johnson syndrome-toxic epidermal necrolysis overlap syndrome
695.15 Toxic epidermal necrolysis
L51.1 Stevens-Johnson syndrome
L51.3 Stevens-Jo...
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1.70. One month after the acute onset of Stevens-Johnson syndrome, there is still active conjunctival and corneal inflammation and already significant symblepharon formation.
1.70. One month after the acute onset of Stevens-Johnson syndrome, there is still active conjunctival and corneal inflammation and already...
FIG. 2.13. Stevens-Johnson syndrome. A: Adolescent with Stevens-Johnson syndrome secondary to sulfonamides. Note the involvement of mucous membranes of the mouth. B: Same child. Note the distribution of lesions.
FIG. 2.13. Stevens-Johnson syndrome. A: Adolescent with Stevens-Johnson syndrome secondary to sulfonamides. Note the involvement of mucous...
<bold>Figure 1-3</bold> Ill-appearing child with Stevens-Johnson syndrome. (Courtesy of Joseph Lopreiato, MD.)
<bold>Figure 72-8</bold> Hemorrhagic ulcerative stomatitis in SJS. (Courtesy of Joseph Lopreiato, MD.)