Their location can be gonadal or extragonadal.
The numerous histolo...
GCT diagnosis should be considered for any midline tumor.
A history of abnormal sexual development may be an indication of an underlying sex chromosome abnormality associated with an i...
The administration of chemotherapy is based on malignant potential, local tumor extent, surgical outcomes, and the patient’s medical history.
The typical 1st-line chemotherapy regim...
Serial physical exams and imaging studies of primary site
Tumor markers (AFP or β-hCG) if elevated at diagnosis
If chemotherapy or radiation therapy used, need to monitor for secondary mali...
Isaacs H Jr. Perinatal (fetal and neonatal) germ cell tumors. J Pediatr Surg. 2004;39(7):1003–1013. [View Abstract on OvidInsights]
Murray MJ, Halsall DJ, Hook CE, et al. Ident...
199.1 Other malignant neoplasm without specification of site
238.0 Neoplasm of uncertain behavior of bone and articular cartilage
164.9 Malignant neoplasm of mediastinum, part unspecified
183.0...
Q: What is the chance of cure for immature/malignant teratomas?
A: With current chemotherapy as outlined earlier, overall survival is 85–97% (dependent on disease stage).
Q: Can a benign tumor recur...
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