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Thrombosis, Pediatric

Char M. Witmer, MD, MSCE Reviewed 10/2018
 


BASICS

DESCRIPTION

Pathologic arterial or venous intravascular occlusion secondary to abnormal thrombus formation. The following are common thrombotic events: 
  • Deep venous thrombosis (DVT): involves lar...

DIAGNOSIS

Approach to patient 
  • Phase 1

    • Perform complete history and physical exam.

    • Establish diagnosis using the appropriate radiographic study.

  • Phase 2

    • Send initial laboratory studies (CBC, PT/aPTT, D-dim...

TREATMENT

GENERAL MEASURES

  • Therapy for acute thrombosis and long-term management is individualized.

  • Consult a pediatric hematologist or someone with expertise in pediatric anticoagulant therapy.

MEDICATION

ONGOING CARE

COMPLICATIONS

  • Inferior vena cava filters are used to prevent pulmonary embolism. There are limited pediatric studies. They should only be considered in the setting of a lower extremity DVT...

ADDITIONAL READING

  • Goldenberg N, Bernard T. Venous thromboembolism in children. Pediatr Clin North Am.  2008;55(2):305–322. [View Abstract on OvidInsights]

  • Monagle P, Chan AK, Goldenberg NA, et al...

CODES

ICD9

  • 453.9 Other venous embolism and thrombosis of unspecified site

  • 453.40 Acute venous embolism and thrombosis of unspecified deep vessels of lower extremity

  • 325 Phlebitis and thrombophlebitis of ...

FAQ

  • Q: When is it appropriate to use low-molecular-weight heparin (i.e., enoxaparin) rather than unfractionated heparin?

  • A: There are several advantages to low-molecular-weight heparin. The pharmacokin...

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