Transfusion Reaction, Pediatric

Any acute or subacute adverse reaction that develops as a consequence of the administration of blood components

Types include the following:

• Acute reactions: hemolytic, febrile, allerg...

Acute hemolytic

• Fever/chills

• Abdominal or flank pain

• Pink or tea-colored urine

• Tachycardia

• Hypotension

• Oliguria

FNHTR

• Fever, chills 1 to 6 hours after transfusion

Urticarial

• Urticaria

• Flushing

• Pr...

Acute hemolytic

• Stop transfusion immediately.

• Supportive care with hydration, pressors, and diuretics to maintain circulation and urine output

FNHTR

• Stop transfusion.

• Antipyretics...

Posttransfusion hepatitis: caused by hepatitis B or C viruses, others

AIDS: caused by HIV

Cytomegalovirus (CMV)

• Symptomatic infection in patients with inherited or acquired immu...

Delaney M, Wendel S, Bercovitz RS, et al. Transfusion reactions: prevention, diagnosis, and treatment. Lancet.  2016;388(10061):2825–2836. [View Abstract on OvidInsights]

Lindho...

999.80 Transfusion reaction, unspecified

999.83 Hemolytic transfusion reaction, incompatibility unspecified

999.89 Other transfusion reaction

518.7 Transfusion related acute lung injury (TRALI)

...

Q: What is the risk of acquiring certain viral infections?

A: Hepatitis B: 1:300,000 transfused units; hepatitis C: 1:1,800,000 transfused units; HIV: 1:2,300,000 transfused units

Q: What is the ris...