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Transient Erythroblastopenia of Childhood, Pediatric

Julie W. Stern, MD Reviewed 10/2018
 


BASICS

DESCRIPTION

An acquired, self-limited suppression of red cell production in an otherwise healthy child 

EPIDEMIOLOGY

  • Mean age at diagnosis is 26 months.

  • <10% are >3 years of age at diagnosis.

  • ...

DIAGNOSIS

HISTORY

  • Pallor

    • Typically slow in onset and therefore often missed by parents

    • Often noted by an adult who sees the child less frequently

  • Activity level

    • Often preserved because of slow onset of ane...

TREATMENT

GENERAL MEASURES

  • Normal activity and diet for age, as tolerated

  • Instruct family on signs and symptoms of severe anemia.

MEDICATION

  • No role for prednisone, iron supplements, anabolic steroids, or...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Patient Monitoring

  • Clinic visits weekly to monitor hemoglobin and reticulocytes. These visits may need to be more frequent in the beginning of the illness and less...

ADDITIONAL READING

  • Bhambhani K, Inoue S, Sarnaik SA. Seasonal clustering of transient erythroblastopenia of childhood. Am J Dis Child.  1988;142(2):175–177. [View Abstract on OvidInsights]

  • Huang L...

CODES

ICD9

284.81 Red cell aplasia (acquired)(adult)(with thymoma) 

ICD10

D60.1 Transient acquired pure red cell aplasia 

SNOMED

234375006 Transient erythroblastopenia of childhood (disorder) 

FAQ

  • Q: Can other children in a family get this illness?

  • A: The cause(s) of this illness in otherwise normal children is unknown. It is very rare for other family members to be affected. It is appropria...

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