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Transposition of the Great Arteries, Pediatric

Kim Haberer, MD, FRCPC Reviewed 10/2018
 


BASICS

DESCRIPTION

Abnormal anatomic relationship between the great arteries and the ventricles in which the aorta arises from the anatomic right ventricle and the pulmonary artery arises from the anat...

DIAGNOSIS

HISTORY

  • Infants are of normal birth weight or sometimes large for gestational age.

  • Association with maternal diabetes

  • Cyanosis

  • Tachypnea often without retractions

  • Poor feeding

PHYSICAL EXAM

  • General

    • ...

TREATMENT

MEDICATION

  • Correction of metabolic acidosis, hypoglycemia, and hypocalcemia improves myocardial function. The neonate may require fluid resuscitation.

  • Prostaglandin E1 (PGE1) is used for sever...

ONGOING CARE

PROGNOSIS

  • Without treatment, mortality is 30% within the 1st week of life, 50% within the 1st month, 70% within the first 6 months, and 95% within the 1st year.

  • In most centers, the mortali...

ADDITIONAL READING

  • Bellinger DC, Wypij D, duPlessis AJ, et al. Neurodevelopmental status at eight years in children with dextro-transposition of the great arteries: the Boston Circulatory Arrest Trial...

CODES

ICD9

  • 745.10 Complete transposition of great vessels

  • 745.12 Corrected transposition of great vessels

ICD10

  • Q20.3 Discordant ventriculoarterial connection

  • Q20.5 Discordant atrioventricular connection

ICD10

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