Increased production of ketone bodies due to:
Dehydration (nausea/vomiting, ADH inhibition) leads to increased stress hormone production leading to ketone formation
Depleted glycogen s...
Fever absent unless there is an underlying infection
Tachycardia (common) due to:
Dehydration with associated orthostatic changes
Concurrent alcohol withdrawal
Supportive measures including IV access with 0.9 NS, oxygen, and cardiac monitoring
Search for historical clues that may suggest other etiologies such as toxic ingestions or diabe...
Persistent metabolic acidosis
Persistent signs of hypovolemia
Persistent nausea and vomiting
Abdominal pain of uncertain etiology
Comorbid illness requiring admissio...
Aggressive volume repletion with dextrose containing fluid is key.
Volume resuscitate with NS as necessary
Monitor electrolytes before and after treatment.
Cartwright MM, Hajja W, Al-Khatib S, et al. Toxigenic and metabolic causes of ketosis and ketoacidotic syndromes. Crit Care Clin. 2012;28(4): 601–631.
Diltoer M, Troubleyn ...
55571001 alcoholic ketoacidosis (disorder)
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