Absence of menstruation
No spontaneous uterine bleeding by age 16 yr or within 5 yr of breast development, which should occur by age 13.
Menarche and menstrual history
Exercise, weight loss
Previous CNS radiation or chemotherapy
Pregnancy is the most relevant etiology of amenorrhea in the emergency department.
Urine pregnancy test (UPT) may give false negative with low urine specific gravity.
Heiman DL. Amenorrhea. Prim Care Clin Office Pract. 2009;36:1–17.
Lentz G, Lobo R, Gershenson D, et al. Comprehensive Gynecology, 6th ed. Philadelphia, PA: Mosby; 2012.
256.8 Other ovarian dysfunction
626.0 Absence of menstruation
N91.0 Primary amenorrhea
N91.1 Secondary amenorrhea
N91.2 Amenorrhea, unspecified
E28.8 Other ovarian dysfunction
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