Antidepressants are the most commonly prescribed psychiatric medications in US.
Patients who overdose on antidepressants may be on various antidepressants, divided into SSRIs, SNRIs, ...
Traditional SSRIs (fluoxetine, paroxetine, sertraline):
In single substance overdose, rarely will cause severe medical effects
In cases of suspected overdose, bring all medication bottles to hospital with patient.
0.9% NS IV fluids as needed for hypotension
Benzodiazepines as needed for seizures
24 h telemetry admission for ingestions of the following: Citalopram, escitalopram, venlafaxine, desvenlafaxine, bupropion
Asymptomatic patients 6 hr after ingest...
For QRS widening, administer sodium bicarbonate IV bolus.
Overdose with citalopram, venlafaxine, and bupropion have the possibility of being more severe than overdoses with other SS...
Boyer EW, Shannon M. The serotonin syndrome. N Engl J Med. 2005;352(11):1112–1120.
Cooke MJ, Waring WS. Citalopram and cardiac toxicity. Eur J Clin Pharmacol. 2013;69...
969.00 Poisoning by antidepressant, unspecified
969.02 Poisoning by selective serotonin and norepinephrine reuptake inhibitors
969.05 Poisoning by tricyclic antidepressants
969.03 Poisoning by ...
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