Potentiates the activity of γ-aminobutyric acid (GABA), the major inhibitory neurotransmitter, by binding to its own specific site
Also facilitates GABA binding to its site
Results in ...
Midrange or small pupils
Slowed voluntary movements
Attention to airway and breathing
Rapid glucose determination
Obtain pill bottles/pills in suspected overdose
Persistent or profound CNS depression
Cardiovascular or respiratory compromise
Coingestants with potential delayed toxicity
Can discharge after 4-...
Isbister GK, O’Regan L, Sibbritt D, et al. Alprazolam is relatively more toxic than other benzodiazepines in overdose. Br J Clin Pharmacol. 2004;58:88–95.
Lee DC, Ferguson ...
T42.4X1A Poisoning by benzodiazepines, accidental, init
T42.4X2A Poisoning by benzodiazepines, intentional self-harm, init
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