Hypertrophic cardiomyopathy (HCM):
Genetic disorder affecting the sarcomere:
Many phenotypic variations
Hypertrophied (regionally or globally), nondilated left or, rare...
Obstructive symptoms correlate with exertion or suddenly assuming upright position—activities that decrease venous return or ventricular filling.
Severity depends on ...
Unexplained syncope, especially in younger adults.
Hemodynamically significant tachydysrhythmia
Increasing awareness of genetic and phenotypic variants with implications in definition of “normal variant”:
Some authors advocate cardiac ECHO screening for any youth participation...
Bos JM, Ommen SR, Ackerman MJ. Genetics of hypertrophic cardiomyopathy: One, two, or more diseases? Curr Opin Cardiol. 2007;22(3):193–199.
Drezner JA, Ashley E, Baggish A...
233873004 Hypertrophic cardiomyopathy (disorder)
Sign up for a 10-day FREE Trial now and receive full access to all content.