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Dengue Fever, Emergency Medicine

Reviewed 06/2017



  • Dengue fever occurs secondary to dengue viral infection.

  • Most prevalent mosquito-borne viral infection.

  • Poorly understood immunopathologic response causes dengue hemorrhagic fever (DHF...


Signs and Symptoms

  • Fever:

    • Abrupt in onset rising to 39°C or higher

    • 2–7 days duration

    • Biphasic (“saddleback”) curve, returning to almost normal after 2–7 days

    • Associated with frontal or retro-orbi...


Initial Stabilization/Therapy

  • IV access

  • IV crystalloids for hypotension

  • O2 and monitor for unstable patients

Ed Treatment/Procedures

  • Treatment is supportive.

  • IV fluids

  • Acetaminophen (Tylenol) for f...



Admission Criteria

  • ICU admission for the following:

    • Hypotension

    • DIC

    • Thrombocytopenia

    • Hemoconcentration

  • Regular admission for the following:

    • 15 yr of age or younger

    • All patients with previ...

Pearls and Pitfalls

  • Consider dengue in patients presenting with fever and rash who recently traveled to endemic regions.

  • Chikungunya fever is an emerging infectious disease also seen in travelers and m...

Additional Reading

  • Halstead  SB: Dengue. Lancet.  2007;370:1644–1652.

  • Istúriz  RE, Gubler  DJ, Brea del Castillo  J. Dengue and dengue hemorrhagic fever in Latin America and the Caribbean. Infect ...



061 Dengue 


A90 Dengue fever [classical dengue] 


  • 38362002 Dengue (disorder)

  • 20927009 Dengue hemorrhagic fever (disorder)

  • 409671005 Dengue shock syndrome

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