Decrease in effective circulating insulin
Increase in counter regulatory hormones including glucagon, catecholamines, cortisol, and growth hormone
Hyperglycemia owing to:
Polyuria (may have good urine output despite dehydration)
Malaise, weight loss
Initial presentation in 20–40% of patients
Often associated with...
Establish IV access and initiate fluid therapy.
IV access and volume resuscitation
Altered mental status
Shock or cardiac dysrhythmia
Initial glucose >700 mg/dL
Initial pH <7
Risk factors for cerebral edema (age <5 yr, prolong...
Mortality from DKA is predominately related to the occurrence of cerebral edema. Therefore, early and appropriate treatment is of most importance in managing children with DKA.
Al Hanshi S, Shann F. Insulin infused at 0.05 versus 0.1 units/kg/hr in children admitted to intensive care with diabetic ketoacidosis. Pediatr Crit Care Med. 2011;12:137–14...
250.01 type I diabetes mellitus [insulin dependent type] [IDDM] [juvenile type], not stated as uncontrolled, without mention of complication
250.03 Diabetes mellitus without mention of compli...
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