Increased serum IgA:
Circulating IgA complexes
Glomerular mesangial deposition of IgA
Although cause is undefined, there are many associated conditions:
Well-appearing child, despite nature and extent of rash
Recent or current upper respiratory tract infection
Hypertension, if associated renal fa...
IV fluids for shock
Packed RBCs for massive GI hemorrhage
Emergent intervention for life-threa...
Severe abdominal pain
Evidence of renal failure
Normal platelet count
Normal renal function
Minimal or no abd...
Exclude life-threatening causes
NSAIDs are usually adequate
Most patients do not require systemic corticosteroids as it has not been shown to affect the prognosis of HSP nephritis
Chang WL, Yang YH, Wang LC, et al. Renal manifestations in Henoch-Schonlein purpura: A 10-year clinical study. Pediatr Nephrol. 2005;20:1269–1272.
Chartapisak W, Opastiraku...
191306005 Henoch-Schonlein purpura (disorder)
239946005 Postinfective Henoch-Schönlein purpura
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