Acute inflammatory process involving multiple organs
Leading cause of childhood-acquired heart disease in developed countries
Vasculitis is most severe in medium-sized arteries
Classic diagnostic criteria:
Fever for 5 days + 4 of the 5 following criteria:
Bilateral conjunctival injection
Changes in oral mucosa
Polymorphous erythematous rash
Changes in hands or feet—edem...
Initiate IV gammaglobulin (IVIG) and aspirin therapy:
Do not generally need ...
Admit all patients who fulfill diagnostic criteria for Kawasaki disease
Admit toxic-appearing patients who do not yet meet the criteria for Kawasaki disease
Prompt diagnosis and therapy can prevent coronary aneurysms in 95%
Aspirin and IVIG are mainstays of therapy
Must consider the diagnosis in febrile children presenting to the ED for ...
Ashouri N, Takahashi M, Dorey F, et al. Risk factors for nonresponse to therapy in Kawasaki disease. J Pediatr. 2008;153:365–368.
Gerding R. Kawasaki disease: A review. J P...
429.0 Myocarditis, unspecified
446.1 Acute febrile mucocutaneous lymph node syndrome [MCLS]
447.6 Arteritis, unspecified
420.90 Acute pericarditis, unspecified
I51.4 Myocarditis, unspecifie...
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