Neoplasms of WBCs that have undergone a malignant transformation
Occurs with WBC >100,000/mm3
Leads to occlusions of small vessels primarily in brain or lungs
Left upper quadrant pain, tenderness
Splenomegaly (most common)
100% oxygen for hypoxia/shortness of breath
IV access with 0.9% NS
Initiate platelet transfusion for severe bleeding from thrombocytopenia.
Begin broad-spectrum ant...
Newly diagnosed leukemia with:
ICU admission for unstable patients with disseminated intravascular coagulation, bl...
Monitor for tumor lysis and secondary hyperkalemia.
Hyperleukocytosis may present as respiratory failure or hemorrhage.
Abramson N, Melton B. Leukocytosis: Basics of clinical assessment. Am Fam Physician. 2000;62:2053–2060.
Higdon ML, Higdon JA. Treatment of oncologic emergencies. Am Fam Phy...
204.10 Chronic lymphoid leukemia, without mention of having achieved remission
205.10 Chronic myeloid leukemia, without mention of having achieved remission
208.90 Unspecified leukemia, withou...
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