Skip to main content

Mononucleosis, Emergency Medicine

Reviewed 06/2017
 


Basics

Description

  • Results in most cases from infection with the Epstein–Barr virus (EBV) (a herpesvirus):

    • Non-EBV causes of infectious mononucleosis (IM):

      • Cytomegalovirus (CMV)

      • Adenovirus

      • Hepatitis A

      • Herpe...

Diagnosis

Signs and Symptoms

History

  • Typically an insidious onset over several days to weeks but may be abrupt onset

  • Prodromal fatigue, malaise, arthralgias, and myalgias with a biphasic or “waxing and w...

Treatment

Pre-Hospital

  • Follow standard universal precautions

  • ABCs. Assess airway patency

  • Initiate IV hydration with normal saline if patient is dehydrated

Initial Stabilization/Therapy

  • ABC management. Airw...

Follow-Up

Disposition

Admission Criteria

  • Significant airway edema that represents any level of potential airway compromise

  • Neurologic or severe hematologic/hepatic complications

  • Inability to take PO

  • Pain c...

Pearls and Pitfalls

  • Although usually self-limited, significant complications occur and require consultation

  • Treatment with steroids may be useful but is controversial due to potential increased risk of...

Additional Reading

  • American Academy of Pediatrics. Red Book: 2013 Report of the Committee on Infectious Disease. 29th ed. Elk Grove Village, IL: American Academy of Pediatrics; 2012.

  • Auwaerter  PG. R...

Codes

ICD9

075 Infectious mononucleosis 

ICD10

  • B27.00 Gammaherpesviral mononucleosis without complication

  • B27.10 Cytomegaloviral mononucleosis without complications

  • B27.90 Infectious mononucleosis, unspeci...

Subscribe to Access Full Content

Sign Up for a 10-Day Free Trial

Sign up for a 10-day FREE Trial now and receive full access to all content.

×