Optic nerve dysfunction due to an inflammatory process, commonly associated with myelin destruction
Highly associated with multiple sclerosis (MS); presenting feature in 15–20% of MS ...
Vision loss and pain most common symptoms
Visual loss occurring over days (rarely over hours), peaks in 1–2 wk:
Adults usually unilateral (70%)
Bilateral visual loss more comm...
Early ophthalmologic and neurologic consultations
IV steroid pulse followed by oral steroids:
Recommended for those with ≥2 demyelinating lesions on MRI without a prior ...
Bilateral vision loss
If other sources of acute vision loss cannot be ruled out
IV steroid pulse treatment needed
Unilateral visual impairment
Rule out space-occupying lesions before making the diagnosis of optic neuritis.
Acute bilateral loss with a severe headache or diplopia should raise concern for pituitary apoplexy.
Abou Zeid N, Bhatti MT. Acute inflammatory demyelinating optic neuritis: Evidence-based visual and neurological considerations. Neurologist. 2008;14:207–223.
Balcer LJ. Clin...
377.30 Optic neuritis, unspecified
377.31 Optic papillitis
377.32 Retrobulbar neuritis (acute)
377.39 Other optic neuritis
H46.00 Optic papillitis, unspecified eye
H46.9 Unspecified optic ne...
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