Respiratory alkalosis and metabolic acidosis:
Secondary to inhibition of Krebs cycle and uncoupling of oxidative phosphorylation
Dehydration, hyponatremia or hypernatremia, hypokalemia...
Noncardiogenic pulmonary edema
Ask if taking aspirin or aspirin ...
Management of airway, breathing, and circulation (ABCs)
Monitor patients with salicylate levels >25 mg/dL until level drops <25 mg/dL and symptoms abate.
Salicylate levels increasing after having trended downward...
Patients need to maintain their respiratory drive to reverse acidemia, respiratory acidosis:
Do not intubate prematurely.
It is extremely difficult to achieve and maintain mechanical...
Kent K, Ganetsky M, Cohen J, et al. Non-fatal ventricular dysrhythmias associated with severe salicylate toxicity. Clin Toxicol (Phila). 2008;46:297–299.
Stolbach AI, Hoffm...
965.1 Poisoning by salicylates
T39.011A Poisoning by aspirin, accidental (unintentional), init
T39.012A Poisoning by aspirin, int...
Sign up for a 10-day FREE Trial now and receive full access to all content.