Acanthosis nigricans (AN) is a benign dermatosis characterized by velvety, hyperpigmented, hyperkeratotic plaques, which
Are usually symmetric
Most often occur on the posterior neck,...
Age of onset
Most common between the ages of 11 and 40 years
Occurrence in infancy suggests familial or syndromic AN.
Malignant AN is more common in older adults.
Past medical history
Improvement of AN in obese individuals who succeed at weight loss
Discontinue offending drugs in drug-induced AN (1)[B].
Improvement of malignant AN with treatment of underlyin...
Close monitoring of BMI, glycohemoglobin, and blood pressure in obese individuals and those with insulin resistance
Close follow-up and appropriate interventions i...
Romo A, Benavides S. Treatment options in insulin resistance obesity-related acanthosis nigricans. Ann Pharmacother. 2008;42(7):1090–1094. [View Abstract on OvidMedline]
L83 Acanthosis nigricans
Q82.8 Other specified congenital malformations of skin
701.2 Acquired acanthosis nigricans
757.39 Other specified anomalies of skin
72129000 acquired acanthos...
AN is a benign dermatosis that is commonly associated with hyperinsulinemia and may be a useful indicator of diabetes mellitus.
It may also be a marker of malignancy.
AN due to obesity, ...
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