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Chemotherapy-Related Mucositis

Eric L. Fisher, MD and Steven A. House, MD, FAAFP, FAAHPM Reviewed 06/2019
 


BASICS

DESCRIPTION

  • A condition affecting any part of the alimentary tract (most commonly the oral cavity), associated with chemotherapy

  • Mucositis ranges from erythema to erosion to ulceration, causing p...

DIAGNOSIS

HISTORY

  • Clinical diagnosis is made based on the appearance of oral mucosal changes and pain or GI symptoms within 7 days of initiation of chemotherapy or radiation treatment.

  • Pain, odynophagia...

TREATMENT

GENERAL MEASURES

Mucositis often treated by oncologists. Treatment involves pain control, nutritional support during periods of decreased oral intake, prevention of and monitoring for seconda...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Patient Monitoring

Pain, hydration, and nutrition status 

DIET

  • Avoid foods that require significant chewing.

  • Bland—avoid dry, acidic, spicy, or salty foods.

  • Frequent i...

REFERENCES

1
Lalla RV, Sonis ST, Peterson DE. Management of oral mucositis in patients who have cancer. Dent Clin North Am.  2008;52(1):61–77, viii. [View Abstract on OvidMedline]
2
O’Brien CP. Mana...

ADDITIONAL READING

  • Chaveli-López B, Bagán-Sebastián J. Treatment of oral mucositis due to chemotherapy. J Clin Exp Dent.  2016;8(2):e201–e209. [View Abstract on OvidMedline]

  • National Cancer Instit...

CODES

ICD10

K12.31 Oral mucositis (ulcerative) due to antineoplastic therapy 

ICD9

528.01 Mucositis (ulcerative) due to antineoplastic therapy 

SNOMED

109256003 Mucositis following chemotherapy (disorder) 

CLINICAL PEARLS

  • Mucositis often occurs in patients receiving chemotherapy and usually involves the mouth, but it can affect any part of the GI tract.

  • No clinically effective prophylaxis is available.

  • Mo...

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